GPC2-CAR T cells tuned for low antigen density mediate potent
Por um escritor misterioso
Last updated 18 junho 2024
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S1535610821006589-gr7.jpg)
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41586-023-05707-3/MediaObjects/41586_2023_5707_Fig2_HTML.png)
CAR immune cells: design principles, resistance and the next generation
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-023-40115-1/MediaObjects/41467_2023_40115_Fig6_HTML.png)
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S1535610821006589-gr4.jpg)
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://www.tandfonline.com/action/showGraphicalAbstractImage?doi=10.1080%2F08830185.2022.2102619&id=iiri_a_2102619_uf0001_c.jpg)
Full article: B7-H3-targeted CAR-T cell therapy for solid tumors
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S1535610821006589-gr6.jpg)
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S1535610821006589-gr8.jpg)
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S2666379123003798-gr6.jpg)
Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41571-022-00704-3/MediaObjects/41571_2022_704_Fig1_HTML.png)
Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs40364-022-00434-9/MediaObjects/40364_2022_434_Fig1_HTML.png)
Strategies to enhance CAR-T persistence, Biomarker Research
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://www.mdpi.com/vaccines/vaccines-08-00753/article_deploy/html/images/vaccines-08-00753-g002.png)
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